Survival and epidemiological, social, economic and clinical aspects of pediatric peritoneal dialysis: An integrative review

Introduction: The kidneys are fundamental organs for survival and the progressive loss of their functions causes regulatory, excretory endocrine functions, essentially affecting entire balance organism. Chronic Kidney Disease (CKD) is considered a complex disease worldwide public health problem with number patients continuously increasing, even in pediatric population. CKD often progresses to end-stage requiring Renal Replacement Therapy (RRT). transplantation treatment choice maximize survival, growth, development patients, however, if dialysis necessary, Peritoneal Dialysis (PD) high-quality low-cost RRT modality preferred therapy children adolescents End-Stage (ESKD). In this scope, study aimed carry out an integrative review epidemiological, clinical, social economic profile PD. Methods: It whose data collection was carried between January 2019 2021 following methodology suggested by literature, using validated instrument. science descriptors (DECs) from VHL portal (virtual library) were used: children, adolescents, chronic peritoneal dialysis, epidemiology. Results: Thirty-five studies selected evaluated Critical Appraisal Skills Program (CASP). level evidence articles assessed Grading Recommendations Assessment, Development Evaluation (GRADE) scale. Survival social, clinical aspects PD Brazil have been described reviewed. Conclusions: complexity costs involved care impact survival. Mortality morbidity higher than healthy life expectancy considerably lower. ESKD more severe population interferes general development, weight height gain, regulation mineral metabolism definitive cardiovascular calcifications. growth patients. However, necessary first-choice Unfortunately, scarce literature on its aspects.